He succeeds Erkinjon Turdimov, who led the region from January 2025 until his recent appointment as First Deputy Prime Minister and Minister of Education and Science.

Before joining the Presidential Administration, Kodirov held several senior positions in the Interior Ministry. He headed the Main Directorate for Transport Security and, from 2018 to 2019, the Main Directorate for Combating Terrorism and Extremism.

In January 2021, he became deputy presidential adviser on coordinating the activities of law enforcement and supervisory bodies. He was promoted to presidential adviser in the same area in August 2023.

In July 2025, Kodirov left the presidential adviser post and was appointed head of the Department for Public Security and the Rule of Law at the Presidential Administration.